Missouri Qualified Research Expense Tax Credit Program

The Missouri Qualified Research Expense Tax Credit Program provides incentives for additional research expenses for tax years beginning on or after January 1, 2023, for tax years beginning on or after January 1, 2023. Taxpayers may be authorized to receive a credit against the Missouri corporate income tax and financial institutions tax equal to 15% of a taxpayer’s “additional qualified research expenses” or the credit is increased to 20% if such expenses relate to research conducted in conjunction with a public or private Missouri college or university. The highest amount of credit a single taxpayer may claim in one year is $300,000 and the aggregate of all tax credits shall not exceed $10 million in any single year. The $5 million of all tax credits is set aside for small, minority, and women-owned businesses.  Eligible applicants include organizations or entities exempt from federal income tax or any business in good standing with the Secretary of State.

The Qualified Research Expense Tax Credit (QRE) Program cycle for the 2024 tax year was open August 1, 2025, through September 30, 2025, for applications via Submittable.

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